Investigating the role of Hsp90 in the nucleus

I am a biology major currently finishing my chemistry degree requirements at St Andrews University, Scotland. For the past couple of years, I have become intrigued with new discoveries in scientific journals concerning phenotypic plasticity, miRNA regulation, agouti mice, and modification of histone tails.  Epigenetics fascinates me. The more I learn, the more I look for ways to be part of epigenetic research.  As I look ahead to Summer 2014, I am excited to begin studying the heat shock protein 90 (Hsp90) as it interacts with the chromatin. I am interested in how Hsp90’s function at the nucleus is affected when the cellular environment changes during stress, aging, and disease. At the Max Planck Institute of Immunobiology and Epigenetics (MPI-IE), Freiburg, Germany, I will try to unveil the difference between Hsp90 in the nucleus and the Hsp90 in the cytosol. This project is the perfect way to continue learning about the complexity of genetics. I am excited and honored to have the opportunity to contribute to the understanding of the function of Hsp90 in the cell.

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