Characterizing Immune Cells in Rainbow Trout Organs: Abstract

The immune system is an indispensable part of all living organisms. By studying the immune system of certain organisms, we can analyze how changes in our environment can affect the health of biological organisms and predict possible effects on human health, as well. Fish, especially the rainbow trout, can serve as a relevant model because of the rainbow trout’s prevalence in our environment and its influence on humans, whether it may involve environmental detection/sensing or providing insight into the immune system of aquatic organisms. Despite this, the rainbow trout’s immune system is still largely unexplored in the biomedical field, and I intend to contribute┬ámore information and knowledge about this topic for the benefit of humankind.

With the guidance of Dr. Gi Sang Yoon and Dr. Patty Zwollo, my research will provide foundational studies on the detection and characterization of immune cells of the rainbow trout fish’s organs, such as: liver, spleen, anterior kidney, and posterior kidney. Through the use of immune cell-specific antibodies to mark immune cells in situ and miscopy to acquire images, we plan to detect and distinguish the innate and adaptive immune cells in the specified organs of the rainbow trout. The ultimate goal of this research is to gain information that will allow the biomedical field to enhance the knowledge of the immune system of vertebrate animals, in order to develop improved therapies and disease management methods.