Evolving Yeast for Plastic Adherence

Humans, bacteria, and other microbes like yeast live together in a delicate balance, all fighting to survive. However, this balance can easily be shifted. A normal commensal microbe can quickly turn into an opportunistic pathogen presenting problems for human health. In a hospital setting, this becomes a grave health concern for those that are already immune-compromised.

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A Testable Computational Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is characterized by the progressive neurodegeneration of the motor system, clinically described as the degeneration of both upper motor neurons and lower motor neurons. ALS involves the impairment of muscle nourishment, resulting in a progressive loss of voluntary muscle function, and eventually the inability to speak, eat, or breathe.  Research on this fatal disease concentrates around several intertwined areas of concern, including disease diagnosis and progression, therapies for primary and secondary consequences of ALS phenotypes, and identification of its cause (Kiernan et al., 2011, p. 942). Currently, the field has identified several genetic and mechanistic factors implicated in ALS development; cell death in ALS patients has been linked to irregularities in glutamate, a vital neurotransmitter, in calcium function, and to several genetic mutations (Corcia et al., 2017, p. 255). Because neither the cause nor cure of ALS has yet been uncovered, persistent and synergistic research must continue in order to advance the understanding of this disease and contribute to methods of prevention, alleviation, and treatment. In concert with the growing literature on the pathogenesis and progression of ALS, I plan to generate a math-based, research-driven model of the disease at the molecular level to aid the understanding of the disease state of the cell and to test various trigger points and possible treatments.

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Abstract: Divine Depictions of Livia in Early Imperial Statuary and Literature

Marble statue of Livia depicted as Ceres from the Louvre Museum, Paris, France

Marble statue of Livia depicted as Ceres from the Louvre Museum, Paris, France

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