Immunocytochemistry (ICC) — Post #3

Immunocytochemistry is the backbone of my research and for the last two weeks I have been learning the procedures and methodology behind this important piece of my work here this summer. One of the possible heritable difference between reproductively responsive and non-responsive mice is the difference in the number and activity of GnRH neurons involved in initial stages of the HPG (Hypothalamic-pituitary-gonadal) axis. The way that we see the difference between neurons in the reproductively responsive or non-responsive mice is through immunocytochemistry or ICC. ICC uses engineered antibodies to bind to proteins of interest.

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